Hello my name is Nancy and I love this site. I am and will be adding new stamps to my collection so please use all you wish...

As many of you already know my son was very ill and in need of a kidney..This update is to let you know we are no longer looking for a kidney..My son passed on Sept 6,2011..He is now with Jesus even though my heart is broken I must carry on for him....God Bless you all...And thanks to all that tried to help...
For those that are new to my friends my son was born with Bartters Syndrome..Which means his kidneys released all his electrolytes..I was told he would not see 6 but Jesus blessed us with 30 wonderful though very hard years..We spent lots of time in hospitals and had many close calls but my son was a hero till the end..Some days he could not even walk because of the muscle spasms in his legs..They felt like rocks under his skin..But he still tried to get around himself..I will never stop missing him as we were so close and I will shed tears as they come till the day I pass..My life has changed as I knew it and now I am having a very hard time adjusting to the fact he will never walk through my door or sit in my chair which he spent hours in because he said it was most comfortable place for him..I still find myself looking for him not excepting he is gone..This is the hardest thing a Mother can go through..

My Grandson made this for my son in heaven..Please rate and comment it for him... 
http://bln.gs/b/24g8g2


MY SONS POEM!!!

If tears could build a stairway,

And memories were a lane,

I would walk right up to heaven

To bring you down again.

No farewell words were spoken,

No time to say good-bye.

You were gone before I knew it,

And only God knows why.

My heart ache in sadness

And secret tears still flow,

What it meant to lose you,

No one will ever know.

When I'm sad and lonely,

And everything goes wrong,

I seem to hear you whisper

"Cheer up and carry on."

Each time I look at your pictures,

You seem to smile and say,

"Don't cry, I'm in Heaven now,

We'll meet again someday


Bartter syndrome is a rare inherited defect in the thick ascending limb of the loop of Henle. It is characterized by low potassium levels (hypokalemia)[1] , increased blood pH (alkalosis), and normal to low blood pressure. There are two types of Bartter syndrome: neonatal and classic. A closely associated disorder, Gitelman syndrome, is milder than both subtypes of Bartter syndrome.
Contents
 [hide] 

    1 Features
    2 Diagnosis
    3 Pathophysiology
    4 Treatment
    5 Prognosis
    6 History
    7 Related conditions
    8 References
    9 External links

[edit] Features

In 90% of cases, neonatal Bartter syndrome is seen between 24 and 30 weeks of gestation with excess amniotic fluid (polyhydramnios). After birth, the infant is seen to urinate and drink excessively (polyuria, and polydipsia, respectively). Life-threatening dehydration may result if the infant does not receive adequate fluids. About 85% of infants dispose of excess amounts of calcium in the urine (hypercalciuria) and kidneys (nephrocalcinosis), which may lead to kidney stones. In rare occasions, the infant may progress to renal failure.

Patients with classic Bartter syndrome may have symptoms in the first two years of life, but they are usually diagnosed at school age or later. Like infants with the neonatal subtype, patients with classic Bartter syndrome also have polyuria, polydipsia, and a tendency to dehydration, but normal or just slightly increased urinary calcium excretion without the tendency to develop kidney stones. These patients also have vomiting and growth retardation. Kidney function is also normal if the disease is treated,[2] but occasionally patients proceed to end-stage renal failure. Bartter's syndrome consists of hypokalaemia, alkalosis, normal to low blood pressures, and elevated plasma renin and aldosterone. Numerous causes of this syndrome probably exist. Diagnostic pointers include high urinary potassium and chloride despite low serum values, increased plasma renin, hyperplasia of the juxtaglomerular apparatus on renal biopsy, and careful exclusion of diuretic abuse. Excess production of renal prostaglandins is often found. Magnesium wasting may also occur.
[edit] Diagnosis

People suffering from Bartter syndrome present symptoms that are identical to those of patients who are on loop diuretics like furosemide.

The clinical findings characteristic of Bartter syndrome are hypokalemia, metabolic alkalosis, and normal to low blood pressure. These findings may also be caused by:

    Chronic vomiting: These patients will have low urine chloride levels (Bartter's will have relatively higher urine chloride levels).
    Abuse of diuretic medications (water pills): The physician must screen urine for multiple diuretics before diagnosis is made.
    Magnesium deficiency and Calcium deficiency: These patients will also have low serum and urine magnesium and calcium

Patients with Bartter syndrome may also have elevated renin and aldosterone levels.[3]

Prenatal Bartter syndrome can be associated with polyhydramnios.[4]
[edit] Pathophysiology

Bartter syndrome is caused by mutations of genes encoding proteins that transport ions across renal cells in the thick ascending limb of the nephron.[2]

Bartter and Gitelman syndromes can be divided into different subtypes based on the genes involved:[5]
Name 	Bartter type 	Associated gene mutations 	Defect
neonatal Bartter's syndrome 	type 1 	NKCC2 	Na-K-2Cl symporter
neonatal Bartter's syndrome 	type 2 	ROMK 	thick ascending limb K+ channel
classic Bartter's syndrome 	type 3 	CLCNKB 	Cl- channel
Bartter's syndrome with sensorineural deafness 	type 4 	BSND[6] 	Cl- channel accessory subunit
Bartter's syndrome associated with autosomal dominant hypocalcemia 	type 5 	CASR[7] 	activating mutation of the calcium-sensing receptor
Gitelman's syndrome 	- 	SLC12A3 (NCCT) 	Sodium-chloride symporter
[edit] Treatment

While patients should be encouraged to include liberal amounts of sodium[citation needed] and potassium in their diet, potassium supplements are usually required, and spironolactone is also used to reduce potassium loss.[1]

Nonsteroidal antiinflammatory drugs (NSAIDs) can be used as well, and are particularly helpful in patients with neonatal Bartter's syndrome.

Angiotensin-converting enzyme (ACE) inhibitors can also be used.
[edit] Prognosis

The limited prognostic information available suggests that early diagnosis and appropriate treatment of infants and young children with Classic Bartter Syndrome may improve growth and perhaps neurointellectual development. On the other hand, sustained hypokalemia and hyperreninemia can cause progressive tubulointerstitial nephritis, resulting in end-stage-renal disease (Kidney failure). With early treatment of the electrolyte imbalances the prognosis for patients with Classic Bartter Syndrome is good.


[edit] History

The condition is named after Dr. Frederic Bartter, who, along with Dr. Pacita Pronove, first described it in 1960 and in more patients in 1962.[3][8][9][10]
[edit] Related conditions

    Bartter and Gitelman syndromes are both characterized by hypokalemia, normal to low blood pressure, and hypochloremic metabolic alkalosis.[11]

Pseudo-Bartter’s syndrome is a syndrome of similar presentation as Bartter syndrome but without any of its characteristic genetic defects. Pseudo-Bartter’s syndrome has been seen in cystic fibrosis,[12] as well as in excessive use of laxatives.[13]
[edit] References

    ^ a b "Bartter Syndrome: Tubular and Cystic Kidney Disorders: Merck Manual Home Edition". Retrieved 2007-12-31.
    ^ a b Rodriguez-Soriano J (1998). "Bartter and related syndromes: the puzzle is almost solved". Pediatr Nephrol 12 (4): 315–27. doi:10.1007/s004670050461. PMID 9655365.
    ^ a b Bartter FC, Pronove P, Gill JR Jr, MacCardle RC (1962). "Hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalemic alkalosis. A new syndrome". Am J Med 33 (6): 811–28. doi:10.1016/0002-9343(62)90214-0. PMID 13969763. Reproduced in Bartter FC, Pronove P, Gill JR, MacCardle RC (1998). "Hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalemic alkalosis. A new syndrome. 1962". J. Am. Soc. Nephrol. 9 (3): 516–28. PMID 9513916.
    ^ Dane B, Yayla M, Dane C, Cetin A (2007). "Prenatal diagnosis of Bartter syndrome with biochemical examination of amniotic fluid: case report". Fetal. Diagn. Ther. 22 (3): 206–8. doi:10.1159/000098719. PMID 17228161.
    ^ Naesens M, Steels P, Verberckmoes R, Vanrenterghem Y, Kuypers D (2004). "Bartter's and Gitelman's syndromes: from gene to clinic". Nephron Physiol 96 (3): p65–78. doi:10.1159/000076752. PMID 15056980.
    ^ Zaffanello M, Taranta A, Palma A, Bettinelli A, Marseglia GL, Emma F (2006). "Type IV Bartter syndrome: report of two new cases". Pediatr. Nephrol. 21 (6): 766–70. doi:10.1007/s00467-006-0090-x. PMID 16583241.
    ^ Vezzoli G, Arcidiacono T, Paloschi V, et al. (2006). "Autosomal dominant hypocalcemia with mild type 5 Bartter syndrome". J. Nephrol. 19 (4): 525–8. PMID 17048213.
    ^ Proesmans W (2006). "Threading through the mizmaze of Bartter syndrome". Pediatr. Nephrol. 21 (7): 896–902. doi:10.1007/s00467-006-0113-7. PMID 16773399.
    ^ synd/2328 at Who Named It?
    ^ http://www.whonamedit.com/synd.cfm/2328.html
    ^ Gitelman HJ, Graham JB, Welt LG (1966). "A new familial disorder characterized by hypokalemia and hypomagnesemia". Trans Assoc Am Physicians 79: 221–35. PMID 5929460.
    ^ Royal Brompton & Harefield Hospital > Pseudo-Bartter’s syndrome Retrieved Mars, 2011
    ^ Metyas, Samy; Rouman, Heba; Arkfeld, Daniel G. (2010). "Pregnancy in a Patient With Gouty Arthritis Secondary to Pseudo-Bartter Syndrome". JCR: Journal of Clinical Rheumatology 16 (5): 219–220. doi:10.1097/RHU.0b013e3181e9312a. edit



Please vote on the 2 links below, They are tributes to my son...Thank you.

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THE ACCIDENT
By: Beverly Czerwinski
I was driving down the road last night as I looked into this car,
And saw a child not buckled up as his dad pulled out of the bar.
He had a beer in his hand and wasn't driving very straight,
My heart suddenly filled up with so much anger and hate.
Nobody saw it coming the car began to roll,
And it did not stop until it hit the pole.
Paramedics were called and I stayed there until they came,
Knowing the father was drunk and he was to blame.
The child did not make it and neither did the dad,
It was such a terrible night, everyone was so sad.
This could have been avoided if the dad didn't drink and drive,
That poor little child would still be alive.



A Handy Reference List Of Emergency Phone Numbers:
Problem
 Call:
 
When in sorrow
 John 14
 
When men fail you
 Psalm 27
 
When you have sinned
 Psalm 51
 
When you worry
 Matthew 6:19-34
 
When you are in danger
 Psalm 91
 
When God seems far away
 Psalm 139
 
When your faith needs stirring
 Hebrews 11
 
When you are lonely and fearful
 Psalm 23
 
When you grow bitter and critical
 I Corinthians 13
 
When you feel down and out
 Romans 8:31
 
When you want peace and rest
 Matthew 11:25-30
 
When the world seems bigger than God
 Psalm 90
 
When you want Christian assurance
 Romans 8:1-30
 
When you leave home for labor or travel
 Psalm 121
 
When your prayers grow narrow or selfish
 Psalm 67
 
When you want courage for a task
 Joshua 1
 
When you think of investments and returns
 Mark 10
 
If you are depressed
 Psalm 27
 
If your pocketbook is empty
 Psalm 37
 
If you are losing confidence in people
 I Corinthians 13
 
If people seem unkind
 John 15
 
If discouraged about your work
 Psalm 126
 
If self pride/greatness takes hold
 Psalm 19
 
If you want to be fruitful
 John 15
 
For understanding of Christianity
 II Corinthians 5:15-19
 
For a great invention/opportunity
 Isaiah 55
 
For how to get along with fellow men
 Romans 12
 
For Paul's secret to happiness
 Colossians 3:12-17
 
 
  
 
ALTERNATE NUMBERS:
  
 
For dealing with fear
 Psalm 34:7
 
For security
 Psalm 121:3
 
For assurance
 Mark 8:35
 
For reassurance
 Psalm 145:18
 
PLEASE NOTE:
Emergency numbers may be dialed direct.
No operator assistance is necessary.
All lines to Heaven are open 24 hours a day!


  
 

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coolguyz13

coolguyz13 sagt:

Vor 1970 Tage
I'm back and miss you :)
vicus54

vicus54 sagt:

Vor 2733 Tage
Thanks!
loveblinkmike

loveblinkmike sagt:

Vor 3625 Tage
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for we shall meet again here, and go a little walk
                Kind regards
stina.scott

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Vor 3748 Tage
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